In addition, our previous study demonstrated that Fn14 overcomes cisplatin resistance of high‐grade serous ovarian cancer by promoting Mdm2‐mediated p53‐R248Q ubiquitination and degradation,[13] therefore, we supposed that Fn14 might play a crucial role in regulating metastasis of EOC. This evidence concerns the gene MDM2 and ovarian serous adenocarcinoma.