Conversely, CASP3 rs4647603 was associated with a significant reduction in PCa risk (GG vs. AA, OR = 0.44, 95% CI = 0.26–0.75, Pheterogeneity = 0.647, p = 0.002; GG vs. GA + AA, OR = 0.61, 95% CI = 0.43–0.87, Pheterogeneity = 0.594, p = 0.006; G‐allele vs. A‐allele, OR = 0.82, 95% CI = 0.68–0.99, Pheterogeneity = 0.113, p = 0.041, Figure 7) (Table 2). Here, CASP3 is linked to posterior cortical atrophy.