SLC7A1 and hepatocellular carcinoma: Arginine can be transported across membranes by SLC family proteins.[27] In T cells, hepatocellular carcinoma cells, and chronic lymphocytic leukemia cells, SLC7A1 plays a dominant role in arginine transport.[19, 28, 69] Interestingly, we observed that SLC3A2 was highly expressed in patients with PTCL, and this increased expression was associated with a significantly shorter OS in patients with AITL, though further validation is needed to determine the clinical relevance of SLC3A2 expression in other PTCL subtypes.