Arginine can be transported across membranes by SLC family proteins.[27] In T cells, hepatocellular carcinoma cells, and chronic lymphocytic leukemia cells, SLC7A1 plays a dominant role in arginine transport.[19, 28, 69] Interestingly, we observed that SLC3A2 was highly expressed in patients with PTCL, and this increased expression was associated with a significantly shorter OS in patients with AITL, though further validation is needed to determine the clinical relevance of SLC3A2 expression in other PTCL subtypes. This evidence concerns the gene CCL21 and mature T-cell and NK-cell non-Hodgkin lymphoma.