The tau aggregates found in both PART and AD are identical and composed of paired helical hyperphosphorylated‐tau filaments containing both 3R and 4R tau isoforms,[7, 10] which are even indistinguishable under cryo‐EM.[11] The anatomical distribution and spread of tau pathology in both diseases are similar, resulting in the application of the same tau pathological staging system for both PART and AD.[7, 12] Numerous studies have shown that Aβ pathology can exacerbate tau hyperphosphorylation,[13] theoretically making tau pathology more severe in AD than in PART. The gene discussed is MAPT; the disease is Alzheimer disease.