CDH1 and colorectal carcinoma: EMT facilitates the transition of quiescent epithelial cells into a more mobile and aggressive state and plays a crucial role in CRC development.[29] In WT cells, MEFsMT CM downregulated the epithelial marker E‐cadherin and upregulated the mesenchymal marker, Vimentin compared with those in MEFsWT CM (Figure 4C).