The combination of exosomes derived from dendritic cells, along with P47 (peptide targeting the HCC cells), HMGN1 (recruiting the DC), and AFP212‐A2 (exosomal anchors), on injection, suppressed tumor growth and increased the immune responses through immune‐stimulatory CD8+ effector T‐cell recruitment and IFN‐g along with a decrease in immunosuppressive factors such as TGF‐b and IL‐10 [150]. This evidence concerns the gene TGFB1 and neoplasm.