Dendritic cell‐derived exosomes (DEX), for instance, have shown promise in activating T cells and inducing antitumor responses in HCC by upregulating IFN‐γ and IL‐2 while downregulating inhibitory cytokines like TGF‐β and IL‐10 [143, 144]. This evidence concerns the gene TGFB1 and hepatocellular carcinoma.