Circ_002136 derived from HCC cells Huh7 and HA22T cells increased proliferation, migration, and invasiveness of HCC cells through sponging of miR‐19a‐3p and downregulating RAB1A, which are members of Rab proteins needed for the trafficking of amino acids from the Golgi apparatus and endoplasmic reticulum, along with upregulation of the mTOR signaling pathway for cellular growth and migration [125]. This evidence concerns the gene MTOR and hepatocellular carcinoma.