PIEZO1 and myocardial infarction: It is known that Piezo1 expression is increased in infarct zone, border zone, and remote zone 4 weeks and 8 weeks post‐MI.[5, 9] Typically, devices should be implanted after the cardiac condition stabilizes post‐MI.[36] In this study, patches were applied following LAD ligation, at which time Piezo1 expression has not fully responded to the ischemic event,[5] the patch treatment still reversed the stress‐induced Piezo1 expression in all myocardial regions including infarct zone, border zone and remote zone (Figure S6, Supporting Information).