INSM1 and neoplasm: TR have been reported to be significantly associated with high‐grade tumors (Hyams‐grade III–IV) [34, 44, 45, 66], advanced tumor‐stage [45, 64, 66, 68, 70], expression of the biomarker INSM1 [68], and a reduced survival time [18, 45, 66, 69].