IFNG and neoplasm: Using 10X Genomics Visium spatial transcriptomics, we asked if the IFN-γ-stimulated (Cxcl9+) macrophage population and CTLs were distributed differently between tumors from responder (CC075F1, n = 2) vs. nonresponder strains (CC080F1, n = 2) 2 days after treatment with a single dose of isotype antibodies to represent a pre-aPD1-treated tumor TIME state.