CD4 and Marinesco-Sjogren syndrome: In the MSS patient, we found several markers (FCGR3 A, KLRG1, GZMH, PRSS23, TGFBR3, NUAK1, LINC02384, PDCD1, HIST1H1E, and DUSP5) upregulated in CD8+ and CD4+ EM T cells (Fig. 1e).