In comparing the MSS patient with the patient’s mother (control), we identified abundance of immune cells (Fig. 1c) that reflected a bias towards the CD14+ monocytes I, plasmacytoid dendric cells II and CD4+ naïve T cells (all the three cell types lower in the MSS patient) as well as effector memory either CD4+ or CD8+ (EM; higher in the MSS patient) T cell subsets (Fig. 1d, and Suppl. This evidence concerns the gene CD4 and Marinesco-Sjogren syndrome.