Furthermore, we identified that several genes related to iron export, keratin, inflammation, prostaglandins, and histone modification (SLC40A1, SOCS2, PTGDS, NRGN, TNFRSF4, PTGER2, IER5, and HIST1H1E) that were also upregulated in CD4+ EM T cells in the MSS patient (Fig. 1e). Here, TNFRSF4 is linked to Marinesco-Sjogren syndrome.