High hyperdiploidy and t (12;21) were predominantly found in the age group 1-6 years (P < 0.001), whereas MLL gene rearrangements were predominantly found in infants, representing 58.3% of all infant ALL cases (P < 0.001) (Supplemental Figure 1A(Supplemental Figure 1)). The gene discussed is KMT2A; the disease is acute lymphoblastic leukemia.