Recently, we demonstrated that this is effective to attach the insoluble cancer testis antigen epitope NY-ESO-1 (157-165) to the chemokine XCL1 for targeted delivery to human conventional type 1 dendritic cells (cDC1s).50 PEGylation can induce anti-PEG antibodies in vivo, preventing repeated administration of the vaccine. This evidence concerns the gene XCL1 and cancer.