This study aimed to analyze ML329 action in GIST cell models: imatinib-sensitive GIST-T1 cell line and imatinib-resistant GIST 430/654 (which harbors a KIT mutation in exon 13 (Val654Ala) associated with imatinib resistance in GISTs).15 The gene discussed is KIT; the disease is gastrointestinal stromal tumor.