However, the overall results showed that the difference in TNF-α between the experimental and control groups was statistically significant [MD = −3.20, 95% CI (−4.24, −2.16), P < 0.00001], indicating that Xuanbai Chengqi Decoction has a significant overall effect in the adjunctive treatment of severe pneumonia (Figure 6B). This evidence concerns the gene TNF and pneumonia.