On the other hand, another meta-analysis showed that GLP-1 RAs reduced the risk of CV death [Risk Ratio (RR), 0.90; 95% CI, 0.83–0.97; P = 0.004], and fatal or nonfatal stroke (RR, 0.85; 95% CI, 0.77–0.94; P = 0.001). This evidence concerns the gene GLP1R and stroke disorder.