CD8A and neoplasm: Additionally, Shi et al. discovered that bladder cancer (BCa)-derived exosome circRNA_0013936 upregulates FATP2 via the circRNA_0013936/miR-320a/JAK2 pathway and downregulates RIPK3 through the circRNA_0013936/miR-301b-3p/CREB1 pathway in PMN-MDSCs, resulting in a significant inhibition of CD8+ T cell function and, consequently, tumor immunity (Shi et al., 2024).