During tumorigenesis, cancer cells and associated stromal cells secrete substantial quantities of cytokines (e.g., IL-17A, TGF-β), chemokines (e.g., CXCL1, CXCL2), growth factors (e.g., G-CSF, GM-CSF), as well as lipids, which recruit a large population of neutrophils (SenGupta et al., 2021). This evidence concerns the gene CXCL1 and cancer.