MMP7 and renal cell carcinoma: Simultaneously, overexpression of KCNJ15 leads to the downregulation of N-cadherin, vimentin, and MMP-7 protein expression, indicating that KCNJ15 can hinder RCC cell migration and invasion by suppressing the transition of epithelial cells to mesenchymal cells and downregulating MMP-7 (Liu et al., 2019).