In cancer therapy, curcumin has also been shown to inhibit Akt activation and decrease the expression of cyclooxygenase-2; 5-lipooxygenase; vascular endothelial growth factor; phosphorylated signal transducers and activators of transcription 3; and matrix metalloproteinase-9, while increasing the expression and function of p53 in triggering apoptosis, all of which are closely related to tumorigenesis [9, 10]. Here, TP53 is linked to cancer.