Haeusler et al. (2008), Klehmet et al. (2009), and Vogelgesang et al. (2019) observed a rapid decrease in CD4+ T cells, together with a lack of changes within the CD8+ T cells subgroup. Adamski et al. (2014) did not observe any changes in CD4+ and CD8+ T cells, while Jiang et al. (2017) and Liesz et al. (2009b) showed a decreased number of CD4+ and CD8+ T cells in a population of CD3+ T cells in the acute stroke phase. In Hug et al. (2011) research, no changes in CD4+ after stroke were observed. This evidence concerns the gene CD4 and stroke disorder.