INS and pancreatic insulinoma: Gençoğlu et al (2019) showed that the ligands CCL5 (GPR75 agonist), ACEA (CBR1 agonist), exenatide (GLP1R agonist) and CCh (M3R agonist) increased insulin secretion in MIN6 mouse insulinoma cells and that the target receptors of these ligands, GPR75, GPR56, M3R, and GLP1R genes were expressed in those cells.