In 2023, ESHRE, the American Society for Reproductive Medicine (ASRM), the Endocrine Society of the United States (USA), and the European Society of Endocrinology published an updated version of the International Evidence-Based Guidelines for PCOS, These guidelines did not overturn the Rotterdam criteria but, for the first time, explicitly incorporated serum AMH testing into the diagnostic system. This evidence concerns the gene AMH and polycystic ovary syndrome.