Besides coilin, other proteins enriched in the CB include the survival of motor neuron protein (SMN; also known as SMN1), which is mutated in most cases of the neurodegenerative disease spinal muscular atrophy, and WRAP53, which plays a role in the telomerase holoenzyme assembly (Liu and Dreyfuss, 1996; Mahmoudi et al., 2010; Matera and Frey, 1998). The gene discussed is SMN1; the disease is proximal spinal muscular atrophy.