Yes1‐associated transcriptional regulator (YAP1) and WW domain‐containing transcription regulator 1 (WWTR1, also called TAZ), well‐characterised transcriptional effectors of Hippo signalling, have also been implicated as key factors in Sorafenib resistance in hepatocellular carcinoma by increasing SLC7A11 expression.53 Here, WWTR1 is linked to hepatocellular carcinoma.