Cancer cell proliferation can be stimulated by a variety of growth-promoting receptors of exogenous hormones (e.g., progesterone, androgen and insulin) and locally produced growth factors (GF) such as neuregulins (NRGs), epidermal growth factor (EGF), insulin-like growth factors (IGFs), fibroblast growth factors (FGFs), and transforming growth factor β members (TGFβ) (Almaraz Postigo and Montero, 2023; Masuda et al, 2012; Christopoulos et al, 2015; Santolla and Maggiolini, 2020; Kretzschmar, 2000). Here, EGF is linked to cancer.