Different adipokines affect hepatic function as presented by Buechler et al.16 In contrast to our findings, Ataseven et al.17 studied ghrelin and leptin levels in cirrhosis and HCC driven on by the hepatitis B and D viruses and found that the groups with liver cirrhosis and those with HCC did not differ in terms of Child score. This evidence concerns the gene GHRL and hepatocellular carcinoma.