Individuals from the single-positive subgroups were more likely to be older(aged > 80 yrs), dependent in IADL (< 24 pts), had poor nutritional status (MNA < 12 pts), lower albumin levels (< 40 g/L), and decreased eGFR (< 45 ml/min/1.73m2), but hypercholesterolemia was less common than subjects from the double-negative subgroup. This evidence concerns the gene ALB and Hypercholesterolemia.