Especially in cancer samples, Vδ1 subset express SH3BGRL3, CYBA, CCL5, CST7, TMSB10, FCGR3A, ZEB2, PRF1, IFITM2, HLA-E genes, whereas Vδ2 cells are marked by CD52, TPT1 and EEF1A1 genes. The gene discussed is PRF1; the disease is cancer.