PIK3CA and cancer: These include several WT genes like miRNA processing genes, MYCN, SIX1/2, and CTNNB1/AMER1, as well as known cancer genes, e.g., TP53, MAP3K4, and PIK3CA. In addition, we found mutations in several genes not yet described as recurrently affected in WT, but with known oncogenic properties in other cancer types (BCL9L, CSE1L, EEF1A1, GNAS, KDM5B, RAI1).