Infection of neutrophils with DD8 failed to demonstrate any features of transdifferentiation as the baseline transdifferentiation frequency of the P1 neutrophil population was 1.21% (1.08%–1.42%) (Fig. 4F and H) which, post-infection, resulted in a small presence of a CD66b+/CD83+ (P1/P3) population, majority remaining CD66b+/CD83- (P1/P4) population, the median transdifferentiation frequency of the CD66b+/CD83+ (P3/P1) population being 9.21% (8.15%–9.29%) (Fig. 4G and H). Here, CEACAM8 is linked to infection.