CASP3 and cancer: Caspase-3 is a key executioner proteasein the apoptotic cascade,playing a crucial role in programmed cell death through the cleavageof structural and regulatory proteins. Due to its central function, the ability to accurately detect andquantify caspase-3 activity is essential for studying apoptosis invarious biological contexts, including cancer, neurodegenerative disorders,and drug-screening applications.−, , ,