For example, Kauppi et al. constructed a six-metabolitepredictive model for bacteremic sepsis, outperforming conventionalbiomarkers like CRP and WBC. Similarly,Langley et al. investigated the plasma metabolome and the clinicalfeatures of patients upon ED arrival. The algorithm, formed from five metabolic features and two clinicalfeatures, demonstrated superior predictive value for sepsis outcomescompared to a traditional marker or the SOFA score. Here, CRP is linked to Sepsis.