It is worth mentioning that the 4 cases with NTRK3 fusions were among those cases that exhibited additional neoplasia: two high initial risk cases with a synchronous tumor, a melanoma or a solid pseudopapillary pancreatic neoplasm; and two intermediate risk cases with a previous medulloblastoma, which also received neck radiotherapy, and an adrenal neuroblastoma. The gene discussed is NTRK3; the disease is neoplasm.