For instance, increased IL-18 levels have been reported in pancreatic ductal adenocarcinoma [47], gastric cancer [48], and cutaneous T-cell lymphoma [49], while IL-1β concentrations were elevated in the peripheral blood of patients with head and neck SCC [50], supporting the relevance of our findings in the context of cancer progression. Here, IL1B is linked to pancreatic ductal adenocarcinoma.