The GBM patients were interrogated using the TCGA dataset to correlate OS with methylation status stratified according to both sex and age at diagnosis to investigate the prognostic impact of TGFB2 (Figure S2A,B), TGFB1 (Figure S2C,D), MGMT (Figure S2E,F), and TGFB3 (Figure S2G,H) methylation in these patients. This evidence concerns the gene MGMT and glioblastoma.