FGFR2 and intrahepatic cholangiocarcinoma: This patient had fluke-associated intrahepatic cholangiocarcinoma and was alive at the time of the report, 38.9 months after diagnosis.12 In another genomic series with exclusively iCCA patients, FGFR2 mutations were observed in 18 of 412 (4.4%) patients.14 None of these patients had the FGFR2 p.Ser252Trp mutation.