Transcription factors like SNAIL and NF-kB, previously linked to miR-146a-5p regulation in other cancers, or rs2910164 polymorphism in pre-miR-146a reported in OSCC patients or activation of TNFα and TGF-β, may contribute to the high expression of miR-146a-5p in SCC-9 OSCC cells [52–54]. The gene discussed is NFKB1; the disease is cancer.