demonstrated the complete eradication of tumors, both at the primary as well as distant sites, following injection of conditionally replication‐competent adenovirus containing mda‐7/IL‐24 (Ad.PEG‐E1A‐mda‐7) into athymic nude mice bearing human breast cancer xenografts (Sarkar et al. 2005). The gene discussed is IL24; the disease is breast cancer.