concluded that glycosylation is not necessary for IL‐24 anti‐tumor activity (Sauane et al. 2006), our own studies showed that IL‐24 phosphorylation is essential for protein secretion, localization, signaling, and anti‐cancer activity (for instance decreased cell proliferation and invasion as well as induction of cell cycle arrest) (Panneerselvam, Shanker, et al. 2015). Here, IL24 is linked to neoplasm.