OSU‐03012 enhanced the IL‐24‐mediated cytotoxicity in GBM cell lines; the combination increased PKR‐PERK while reducing the expression of the anti‐apoptotic proteins MCL‐1 and BCL‐XL, resulting in a profound anti‐tumor effect (Hamed et al. 2010). The gene discussed is IL24; the disease is neoplasm.