Finally, in a clinical setting involving intra‐tumoral administration of adenovirus expressing IL24 (INGN‐241) to cancer patients, greater tumor cell apoptosis was observed at the tumor site and distant sites, underscoring the pronounced bystander effect of IL‐24 in humans (Cunningham et al. 2005; Tong et al. 2005). Here, IL24 is linked to neoplasm.