For example, Chada et al., illustrated that administering adenovirus overexpressing IL‐24 resulted in dose‐ and time‐dependent cytotoxicity in human pancreatic cancer cells (MiaPaCa‐2, AsPc‐1) by regulating Wnt and PI3K pathway proteins (Chada et al. 2005). This evidence concerns the gene IL24 and familial pancreatic carcinoma.