The findings indicated that TMPZ did not significantly affect the viability of in vitro AP cells (Figure 3d) but significantly reduced cytotoxicity (LDH activity, P < 0.001), apoptosis rate (P < 0.001), and levels of inflammatory cytokines IL-1β and IL-18 (P < 0.01) in the model group (Figures 3e–i). This evidence concerns the gene IL18 and alkaline phosphatase measurement.