Terpenoids (e.g., tanshinone IIA) coordinate autophagy-inflammation crosstalk by inhibiting NF-κB/NLRP3, decreasing IL-1β-induced p62 accumulation in podocytes, while triptolide adaptively regulates AMPK/ULK1 to prevent apoptosis in advanced DKD. This evidence concerns the gene NFKB1 and diabetic kidney disease.