β-Asarone modulates the JNK/Bcl-2/Beclin-1 pathway, reducing JNK and p-JNK expression while increasing Bcl-2 and Beclin-1 levels in the striatum of 6-OHDA-induced Parkinson’s model rats, attenuating excessive autophagy (Zhang S. et al., 2016). This evidence concerns the gene MAPK8 and Parkinson disease.