The volatile oil of ATR suppresses hippocampal NF-κB and IKKβ phosphorylation in 3×Tg-AD mice, reducing NLRP3 inflammasome activation and downregulating ASC, caspase-1, and the level of GSDMD-N, thereby exerting neuroprotective effects (Xu et al., 2023). This evidence concerns the gene ATR and Alzheimer disease.