The PSMA positive cases were seen more in stages III and IV and high-grade disease compared with early-stage and low-grade disease, respectively.5A few prior case reports of intrahepatic cholangiocarcinoma detected PSMA PET imaging have been reported.6, 7, 8There are insufficient data to determine if PSMA PET can be reliably used to differentiate between metastases from prostate cancer and primary hepatobiliary malignancies. This evidence concerns the gene FOLH1 and Familial prostate cancer.