A 77-year-old male, follow-up case of adenocarcinoma prostate gland, postmultiple cycles of chemotherapy and radiotherapy and raised total serum PSA level of approximately 152.4 ng/mL, underwent [68Ga] PSMA PET/CT scan for treatment response evaluation and restaging, shown inFig. 5, demonstrated multiple PSMA avid abdomino-pelvis lymph nodes with multiple PSMA avid liver lesions and multiple PSMA avid and non-PSMA avid skeletal lesions, likely metastatic disease. Here, KLK3 is linked to metastatic neoplasm.