PAQR5 and hepatocellular carcinoma: In the HCC cells-PBMC co-culture system, PBMCs repressed the HCC cell viability and promoted apoptosis in control group (Fig S10A-B, Fig S11A-B); overexpression of PAQR5 in HCC cells reversed the repressive effects of PBMCs on cell viability, whereas weakened the facilitation effect on apoptosis (Fig S10A-B).