Furthermore, MCP-1 and IL-18 were lower in LC relative to the what observed in recovered LC individuals, while the level of IL-6, IFN-γ, and IL-8 decreased in the LC cohort compared to the healthy cohort (Kovarik et al., 2023; Williams et al., 2022). This evidence concerns the gene IL18 and laryngotracheoesophageal cleft.