We disclosed IL-1β, IFN-α, IFN-γ, TNF-α, IL-8, IL-12p70, IL-17 A, and IL-23 were significantly higher in LC cohort than in AC cohort, while CCL2/MCP-1, IL-6, and IL-18 were significantly lower than in AC cohort (Fig. 5 Table S9, and Supplementary excel file). This evidence concerns the gene CCL2 and laryngotracheoesophageal cleft.