MAPRE2 and acute myeloid leukemia: The poor prognosis of VAF \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\ge$$\end{document}≥20% is primarily due to the enrichment of MDS-EB2, AML, CK, biallelic, and monoallelic inactivation with CK (Supplementary Fig. 5C–E).