DNMT1 and hepatocellular carcinoma: The light‐activated disruption efficiency of the exogenous sfGFP gene using LAC12aGE machinery (69%) is comparable to the previously reported exogenous gene disruption efficiency using CRISPR/Cas12a system.[50] These include the light‐stimulated disruption of the DNMT1 gene in HEK293T cells, and the knockout of the HGF gene in HCC cells.