PSMB8 and thyroid gland disorder: Subgroup analyses showed a significant association between high PSMB8 expression and improved OS in various clinical subgroups, including the classical histological subtype (Fig 3E), pathological stage III (Fig 3F), M0 stage (Fig 3G), N1 stage (Fig 3H), T3 stage (Fig 3I), with extrathyroidal extension (Fig 3J), without extrathyroidal extension (Fig 3K), residual tumor R0 (Fig 3L), residual tumor R1 (Fig 3M), patients without a history of thyroid gland disorders (Fig 3N), male (Fig 3O), female (Fig 3P), white race (Fig 3Q), and age > 45 (Fig 3R).