Targets also identified by the algorithm were the interacting ligands and receptors of B-cell activating factor (BAFF), a proliferation-inducing ligand (APRIL), B-cell maturation antigen (BCMA), and transmembrane activator and calcium modulating ligand interactor (TACI), which have known relevance to myeloma pathophysiology.15 Here, TNFSF13B is linked to plasma cell myeloma.