Furthermore, the expression of TP53 also increases in Ovarian (OV), Esophageal (ESCA), Rectal Adenocarcinoma (READ), and HNSCC cancers compared to the other 33 tumours studied (Fig 3C), indicating that TP53 dysregulation is a common feature across multiple cancers. This evidence concerns the gene TP53 and rectum adenocarcinoma.