OPN1SW and neoplasm: Trying to identify effective therapeutic protocol for CCA, the tumor antiproliferative activity was investigated using CCA cells and nonmalignant H69 cholangiocytes treated with doxorubicin combined with BCP, where BCP was able to synergize the cytotoxic effect of the low dose doxorubicin in CCA cells, a cytoprotective effects of BCP on the nonmalignant cells were observed.